Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 6/20 | 0.40 |
| ▸ | NOS3 | P29474 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2199916 | 0.98 | SHMT2 (0.50) | SHMT2PRMT6ADRB2ECE2EPHX2 | |
| SCHEMBL25588056 | 0.82 | SHMT2 (0.53) | SHMT2ECE2MAPTNPC1RAB9A | |
| SCHEMBL25584926 | 0.81 | SHMT2 (0.49) | SHMT2ECE2NOS1MAPTNPC1 | |
| SCHEMBL5547086 | 0.80 | SHMT2 (0.51) | SHMT2ECE2MAPTNPC1RAB9A | |
| SCHEMBL25584036 | 0.79 | SHMT2 (0.48) | SHMT2ECE2MAPTNPC1RAB9A | |
| SCHEMBL3005405 | 0.78 | ALDH1A1 (0.53) | MAPTNPC1RAB9AKDM4E | |
| SCHEMBL2206223 | 0.78 | ALDH1A1 (0.53) | PRMT6EPHX2NOS1NOS3NOS2 | |
| SCHEMBL2056360 | 0.77 | NOS3 (0.52) | SHMT2ECE2NOS1NOS3NOS2 | |
| SCHEMBL6762944 | 0.75 | HRH4 (0.49) | SHMT2KDM4EHTR7 | |
| SCHEMBL25783078 | 0.74 | BRAF (0.47) | SHMT2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4082611-A1 | AZETIDINE SULFONAMIDE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2022-11-02 | — | — | EP | disclosed |
| WO-2020133403-A1 | SUBSTITUTED PYRIMIDINE ARYL ESTER DERIVATIVE, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | 青岛清原化合物有限公司 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020006869-A1 | SUBSTITUTED PYRIMIDINYL FORMYL OXIME DERIVATIVE, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2020-01-09 | — | — | WO | disclosed |
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
| WO-2015040425-A1 | RESORCINOL N-ARYL AMIDE COMPOUNDS, FOR USE AS PYRUVATE DEHYDROGENASE KINASE INHIBITORS | VERNALIS (R&D) LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |