Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 16/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585497 | 0.94 | PDK1 (0.47) | PDK1L3MBTL1STK17BSTK17APDK2 | |
| SCHEMBL31380404 | 0.90 | STK17B (0.53) | PDK1L3MBTL1STK17BSTK17AGAA | |
| SCHEMBL16793957 | 0.86 | STK17B (0.44) | PDK1STK17BSTK17APDK2PDK3 | |
| SCHEMBL16586284 | 0.82 | MAPKAPK2 (0.47) | STK17BSTK17ANAMPT | |
| SCHEMBL12921676 | 0.79 | AAK1 (0.53) | L3MBTL1STK17BSTK17AGAANAMPT | |
| SCHEMBL1585183 | 0.77 | STK17B (0.52) | L3MBTL1STK17BSTK17AGAANAMPT | |
| SCHEMBL16038520 | 0.77 | GAA (0.52) | L3MBTL1GAANAMPT | |
| SCHEMBL16794337 | 0.77 | TRPV1 (0.42) | STK17BSTK17A | |
| SCHEMBL3180689 | 0.75 | L3MBTL1 (0.61) | L3MBTL1GAANAMPT | |
| SCHEMBL506742 | 0.75 | L3MBTL1 (0.53) | L3MBTL1STK17BSTK17AGAANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040425-A1 | RESORCINOL N-ARYL AMIDE COMPOUNDS, FOR USE AS PYRUVATE DEHYDROGENASE KINASE INHIBITORS | VERNALIS (R&D) LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |