Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.53 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.40 |
| ▸ | SDC2 | P34741 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585641 | 0.90 | PDK1 (0.51) | STK17BSTK17AL3MBTL1GAANAMPT | |
| SCHEMBL16585497 | 0.84 | PDK1 (0.47) | STK17BSTK17AL3MBTL1NAMPTPDK1 | |
| SCHEMBL6508416 | 0.82 | STK17B (0.49) | STK17BSTK17ACKS1BSKP1SKP2 | |
| SCHEMBL6508410 | 0.80 | STK17B (0.46) | STK17BSTK17ACKS1BSKP1SKP2 | |
| SCHEMBL12921676 | 0.80 | AAK1 (0.53) | STK17BSTK17AL3MBTL1GAANAMPT | |
| SCHEMBL1585183 | 0.78 | STK17B (0.52) | STK17BSTK17AL3MBTL1GAANAMPT | |
| SCHEMBL16038520 | 0.78 | GAA (0.52) | L3MBTL1GAANAMPTATRHDAC1 | |
| SCHEMBL3180689 | 0.76 | L3MBTL1 (0.61) | L3MBTL1GAANAMPTHDAC1MAPT | |
| SCHEMBL506742 | 0.76 | L3MBTL1 (0.53) | STK17BSTK17AL3MBTL1GAANAMPT | |
| SCHEMBL16793957 | 0.76 | STK17B (0.44) | STK17BSTK17APDK1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011445-A1 | PYRIMIDINAMINE NUAK INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 特科罗生物科技(成都)有限公司 | 2025-01-16 | — | — | WO | disclosed |