Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909871 | 0.88 | GSK3B (0.48) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL16175949 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL2902446 | 0.82 | KDM4E (0.60) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL15174164 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL11813953 | 0.79 | KDM4E (0.69) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL910226 | 0.77 | GSK3B (0.58) | ALDH1A1KDM4EHPGDNPSR1MEN1 | |
| SCHEMBL30508474 | 0.77 | HTT (0.57) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL1835974 | 0.77 | PSEN1 (0.45) | KDM4ERAB9ASMN1; SMN2KMT2ACDC7 | |
| SCHEMBL876113 | 0.76 | KDM4E (0.52) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL875685 | 0.76 | KDM4E (0.56) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984093-B1 | METAL COMPLEXES AND USE THEREOF IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-20160308149-A1 | Metal Complexes and Use Thereof in Electronic Devices | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160308149-A1 | Metal Complexes and Use Thereof in Electronic Devices | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACADEMY OF SCIENCES (CN) | 2015-01-08 | — | — | US | disclosed |
| EP-2314588-B1 | 4H-Pyrido[1,2-a]pyrimidin-4-one derivatives as modulators of the estrogen-related receptors | GUANGZHOU INST BIOMED & HEALTH (CN) | 2014-11-05 | — | — | EP | disclosed |
| EP-2314588-B1 | 4H-Pyrido[1,2-a]pyrimidin-4-one derivatives as modulators of the estrogen-related receptors | GUANGZHOU INST BIOMED & HEALTH (CN) | 2014-11-05 | — | — | EP | disclosed |
| WO-2014166577-A1 | METAL COMPLEXES AND USE THEREOF IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2014-10-16 | — | — | WO | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| US-8853221-B2 | Compounds of estrogen-related receptor modulators and the uses thereof | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-07 | — | — | US | disclosed |
| CN-101628913-B | Compounds useful as estrogen-related receptor modulators and uses thereof | GUANGZHOU INST BIOMED & HEALTH | 2013-01-23 | — | — | CN | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE & HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-09-08 | — | — | US | disclosed |
| EP-2314588-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2011-04-27 | — | — | EP | disclosed |
| EP-2314588-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2011-04-27 | — | — | EP | disclosed |
| CN-101628913-A | Compounds useful as estrogen-related receptor modulators and uses thereof | GUANGZHOU INST BIOMED & HEALTH | 2010-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218196-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | ALDH1A1 594/4885KDM4E 1123/4885HPGD 1120/4885 |
| US-20150011544-A1 | COMPOUNDS OF ESTROGEN-RELATED RECEPTOR MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | ALDH1A1 594/4885KDM4E 1123/4885HPGD 1120/4885 |
| US-20160308149-A1 | Metal Complexes and Use Thereof in Electronic Devices | SOD1, SOD3, AP1M1 | ALDH1A1 3181/4885KDM4E 2991/4885HPGD 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.