SCHEMBL16587377

SCHEMBL16587377

C=C(C)C(=O)OCCOC(=S)NC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.46
ALDH1A1 P00352 7/20 0.46
GAA P10253 2/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
ALOX12 P18054 2/20 0.43
LMNA P02545 1/20 0.42
GLA P06280 1/20 0.42
EPHX1 P07099 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MITF O75030 1/20 0.41
ELANE P08246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15399955 0.82 ALDH1A1 (0.57) SMN1; SMN2ALDH1A1GAAKDM4EPOLB
SCHEMBL8913093 0.81 TDP1 (0.48) SMN1; SMN2ALDH1A1KDM4EPOLBTDP1
SCHEMBL20100442 0.78 ATM (0.55) SMN1; SMN2ALDH1A1KDM4ETDP1GLA
SCHEMBL15400292 0.77 MAPT (0.58) SMN1; SMN2ALDH1A1GAAKDM4EPOLB
SCHEMBL436276 0.77 LMNA (0.61) SMN1; SMN2ALDH1A1POLBTDP1APEX1
SCHEMBL17784934 0.77 MAPT (0.54) SMN1; SMN2ALDH1A1POLBTDP1APEX1
Dimethylamine SCHEMBL1021289 0.77 LMNA (0.56) SMN1; SMN2ALDH1A1POLBTDP1APEX1
SCHEMBL14268208 0.75 TDP1 (0.49) SMN1; SMN2ALDH1A1KDM4EPOLBTDP1
SCHEMBL28215252 0.75 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1GAAKDM4ELMNA
Phosphoric Acid SCHEMBL7716499 0.75 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1GAAPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612609-B1 ADHESIVE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2022-12-28 EP disclosed
US-20210171810-A1 Two Step Adhesive System HENKEL AG & CO. KGAA (DE) 2021-06-10 US disclosed
US-20210163799-A1 Two-Part, Cyanoacrylate/Free Radically Curable Adhesive Systems HENKEL AG & CO. KGAA (DE) 2021-06-03 US disclosed
US-10590311-B2 Accelerators for two part curable compositions Henkel IP & Holding GmbH (DE) 2020-03-17 US disclosed
WO-2020037195-A1 TWO-PART, CYANOACRYLATE/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
WO-2020035580-A1 TWO STEP ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed