Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436276 | 0.95 | LMNA (0.61) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL433570 | 0.89 | TDP1 (0.71) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL435195 | 0.89 | TDP1 (0.66) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL9647822 | 0.88 | TDP1 (0.69) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL10790604 | 0.88 | TDP1 (0.69) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL9647846 | 0.88 | TDP1 (0.69) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL28351135 | 0.88 | TDP1 (0.69) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL1696749 | 0.87 | TDP1 (0.54) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL10639863 | 0.87 | LMNA (0.51) | LMNATDP1POLBAPEX1HTT | |
| SCHEMBL116940 | 0.86 | KDM4E (0.53) | LMNATDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101319015-B | Photoradical curable resin composition and method for preparing the composition | SHINETSU CHEMICAL CO | 2013-10-16 | — | — | CN | claimed |
| US-12023392-B2 | Additive manufacturing process | DENTSPLY SIRONA INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11931432-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11925697-B2 | Dental impression material | DENTSPLY SIRONA INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-11918664-B2 | Direct dental filling compositions | DENTSPLY SIRONA INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-11904030-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| EP-3518863-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-11-15 | — | — | EP | disclosed |
| CN-111683640-B | dental composition | 登士柏希罗纳有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20100036075-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2133368-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-12-16 | — | — | EP | disclosed |
| CN-101589075-A | Multi-part redox-curing-type composition | KURARAY MEDICAL INC (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2112178-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2112177-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2108663-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| EP-2108664-A1 | COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| CN-101547930-A | Novel compound, composition containing same, and method for producing polymerizable amide | KURARAY MEDICAL INC (JP) | 2009-09-30 | — | — | CN | disclosed |
| CN-101319015-A | Photoradical curable resin composition and method for preparing the composition | SHINETSU CHEMICAL CO (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1917845-A | One-pack type adhesive composition for dental use | KURARAY MEDICAL INC (JP) | 2007-02-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | LMNA 4196/4885TDP1 950/4885POLB 246/4885 |
| US-11925697-B2 | Dental impression material | FHIT, PASK, TAS2R40 | LMNA 269/4885TDP1 2550/4885POLB 1028/4885 |
| US-11904030-B2 | Dental composition | CBR3, CBR1, PRDX3 | LMNA 4641/4885TDP1 3080/4885POLB 1605/4885 |
| US-11931432-B2 | Dental composition | CAD, MTR, ESD | LMNA 4196/4885TDP1 950/4885POLB 246/4885 |
| US-12023392-B2 | Additive manufacturing process | FLNA, FLNB, SAMM50 | LMNA 52/4885TDP1 3340/4885POLB 1371/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | LMNA 469/4885TDP1 2619/4885POLB 3254/4885 |
| US-11918664-B2 | Direct dental filling compositions | CAD, DOCK5, ITGA5 | LMNA 1540/4885TDP1 3064/4885POLB 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.