⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034588 | 0.79 | — | — | |
| SCHEMBL9780232 | 0.75 | — | — | |
| SCHEMBL11465670 | 0.73 | — | — | |
| SCHEMBL2334872 | 0.72 | — | — | |
| SCHEMBL20656 | 0.70 | TSHR (0.43) | — | |
| SCHEMBL7177724 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL11070461 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL7549527 | 0.70 | TSHR (0.43) | — | |
| SCHEMBL16840065 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL1040655 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2188 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024066986-A1 | 2-AMINOPYRIMIDINE COMPOUND, AND USE AND PHARMACEUTICAL COMPOSITION THEREOF | 楚浦创制（武汉）医药科技有限公司 | 2024-04-04 | — | — | WO | claimed |
| CN-117659345-A | Polyisocyanate curing agent with good matte property and good open-lean storage stability and preparation method thereof | 万华化学集团股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| WO-2023233023-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | UNIVERSITEIT ANTWERPEN (BE) | 2023-12-07 | — | — | WO | claimed |
| CN-115651162-A | Polyisocyanate composition with low free monomer, high compatibility and good open-dilution stability and preparation method thereof | 万华化学集团股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| US-20230000881-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2023-01-05 | — | — | US | claimed |
| EP-3786164-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | Ting Therapeutics LLC (US) | 2021-03-03 | — | — | EP | claimed |
| US-20200179397-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL | 2020-06-11 | — | — | US | claimed |
| US-10676448-B2 | Method for producing TDI-trimerisates with high purity | COVESTRO DEUTSCHLAND AG (DE) | 2020-06-09 | — | — | US | claimed |
| US-10640649-B2 | Solvent-free supersoft and superelastic materials | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2020-05-05 | — | — | US | claimed |
| EP-3334810-B1 | ADDITIVE FOR LUBRICANT COMPOSITIONS COMPRISING A SULFUR-CONTAINING AND A SULFUR-FREE ORGANOMOLYBDENUM COMPOUND, AND A TRIAZOLE | VANDERBILT CHEMICALS LLC (US) | 2020-04-22 | — | — | EP | claimed |
| EP-0078002-A2 | Herbicides containing triazolo(2,3-b)quinazolone as active ingredient, and their use as plant growth regulators | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | claimed |
| US-4370346-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-01-25 | — | — | US | claimed |
| EP-0049728-A2 | Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof | AMERICAN CYANAMID COMPANY (US) | 1982-04-21 | — | — | EP | claimed |
| US-4324717-A | OXIDATION RESISTANCE | THE B. F. GOODRICH COMPANY (US) | 1982-04-13 | — | — | US | claimed |
| EP-0042589-A1 | Norbornene polymers stabilized with hindered aromatic alcohols | The B.F. GOODRICH Company (US) | 1981-12-30 | — | — | EP | claimed |
| US-4265835-A | USING ELECTROMAGNETIC WAVES TO QUANTITATIVELY DETECT THE PRESENCE OF CARBON-B AND THEREBY CONTROL THE MANNICH REACTION OF A CARBOXAMIDE WITH A SECONDARY AMINE AND AN ALDEHYDE | THE DOW CHEMICAL COMPANY (US) | 1981-05-05 | — | — | US | claimed |
| US-4137315-A | ANTIMICROBIAL, ANTIFUNGAL, ANTISEPTICS | RHONE-POULENC INDUSTRIES (FR) | 1979-01-30 | — | — | US | claimed |
| US-4020085-A | 1-(α-Amino-α-phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1977-04-26 | — | — | US | claimed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | claimed |
| US-3935160-A | OXIDATION RESISTANCE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-01-27 | — | — | US | claimed |