SCHEMBL1658824

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30957414	0.83	BAZ2B (0.42)	BAZ2BALDH1A1HPGDKDM4ENPC1
	SCHEMBL15300166	0.83	BAZ2B (0.42)	BAZ2BALDH1A1HPGDKDM4ENPC1
	SCHEMBL5582059	0.83	BAZ2B (0.46)	BAZ2BALDH1A1HPGDKDM4ENPC1
	SCHEMBL4814588	0.79	NPC1 (0.56)	ALDH1A1HPGDKDM4ENPC1RAB9A
	SCHEMBL10620933	0.74	ALDH1A1 (0.58)	ALDH1A1HPGDKDM4ENPC1RAB9A
	SCHEMBL12597861	0.74	CRBN (0.38)	ALDH1A1HPGDKDM4ENPC1RAB9A
	SCHEMBL5726927	0.74	ALDH1A1 (0.34)	BAZ2BALDH1A1HPGDKDM4ENPC1
	SCHEMBL11102779	0.73	ALDH1A1 (0.36)	ALDH1A1HPGDKDM4ENPC1RAB9A
	SCHEMBL9288475	0.72	ALDH1A1 (0.47)	BAZ2BALDH1A1HPGDKDM4ENPC1
	SCHEMBL5727226	0.72	PDE3B (0.38)	BAZ2BALDH1A1HPGDKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.