Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376332 | 0.92 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2FTO | |
| SCHEMBL11687105 | 0.92 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2FTO | |
| SCHEMBL24401902 | 0.85 | FTO (0.47) | LMNAFTOMAPTMEN1KMT2A | |
| SCHEMBL24401887 | 0.85 | FTO (0.47) | LMNAFTOMAPTMEN1KMT2A | |
| SCHEMBL11711333 | 0.84 | LMNA (0.43) | LMNANPC1RAB9ASMN1; SMN2FTO | |
| SCHEMBL16768863 | 0.82 | AVPR1A (0.32) | LMNAFTOMAPTMEN1KMT2A | |
| SCHEMBL16602965 | 0.81 | PARP1 (0.36) | LMNAFTOMAPTMEN1KMT2A | |
| SCHEMBL10013904 | 0.80 | FTO (0.47) | LMNANPC1RAB9AFTOMAPT | |
| SCHEMBL22054775 | 0.79 | NPC1 (0.35) | LMNANPC1RAB9ASMN1; SMN2FTO | |
| SCHEMBL14878228 | 0.76 | LMNA (0.44) | LMNANPC1RAB9ASMN1; SMN2FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399920-B1 | FLUORESCENT PROBE FOR USE IN MEASUREMENT OF PROTEASE | UNIV TOKYO (JP) | 2015-03-25 | — | — | EP | disclosed |