SCHEMBL31376332

SCHEMBL31376332

Nc1ccc2c(c1)Oc1cc(N)ccc1C21OCc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
FTO Q9C0B1 3/20 0.41
OPRD1 P41143 1/20 0.40
MAPT P10636 6/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
GAA P10253 2/20 0.37
HPGD P15428 2/20 0.37
HTT P42858 2/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
SMAD3 P84022 1/20 0.35
PRMT1 Q99873 1/20 0.35
ACE2 Q9BYF1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11687105 1.00 LMNA (0.45) LMNANPC1RAB9ASMN1; SMN2FTO
SCHEMBL16588241 0.92 LMNA (0.40) LMNANPC1RAB9ASMN1; SMN2FTO
SCHEMBL11711333 0.91 LMNA (0.43) LMNANPC1RAB9ASMN1; SMN2FTO
SCHEMBL22054775 0.86 NPC1 (0.35) LMNANPC1RAB9ASMN1; SMN2FTO
SCHEMBL10013904 0.85 FTO (0.47) LMNANPC1RAB9AFTOMAPT
SCHEMBL14878228 0.83 LMNA (0.44) LMNANPC1RAB9ASMN1; SMN2FTO
SCHEMBL10013905 0.82 FTO (0.36) NPC1RAB9AFTOMAPTMEN1
SCHEMBL29558140 0.82 MAOA (0.43) LMNANPC1RAB9ASMN1; SMN2GAA
SCHEMBL3794922 0.82 FTO (0.54) LMNARAB9AFTOMAPTMEN1
SCHEMBL24822228 0.80 AAK1 (0.42) NPC1RAB9ASMN1; SMN2FTOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711470-A1 METHOD AND KIT FOR EVALUATING ENZYME ACTIVITY The University of Tokyo (JP) 2026-03-18 EP disclosed
WO-2025013837-A1 METHOD AND KIT FOR EVALUATING ENZYME ACTIVITY 国立大学法人 東京大学 2025-01-16 WO disclosed