SCHEMBL16588593

SCHEMBL16588593

CCS[C@@H]1OC2COC(c3ccccc3)O[C@H]2C(OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LGALS9 O00182 2/20 0.38
LGALS1 P09382 2/20 0.38
LGALS3 P17931 2/20 0.38
LGALS7; LGALS7B P47929 1/20 0.38
BCHE P06276 5/20 0.37
ALDH1A1 P00352 1/20 0.37
SELP P16109 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16581621 1.00 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL5828119 1.00 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL16593160 1.00 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL13024785 0.95 L3MBTL1 (0.52) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL26491385 0.92 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL20936341 0.92 KMT2A (0.49) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL13024817 0.92 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL18101893 0.92 L3MBTL1 (0.43) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL6704344 0.92 L3MBTL1 (0.50) L3MBTL1KMT2AMEN1LGALS9LGALS1
SCHEMBL6704580 0.92 KMT2A (0.49) L3MBTL1KMT2AMEN1LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170239341-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-08-24 US disclosed
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-09-29 US disclosed
WO-2016046420-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-03-31 WO disclosed
EP-3000820-A1 Synthetic vaccines against Streptococcus pneumoniae serotype 8 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-03-30 EP disclosed
WO-2015040140-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-26 WO disclosed
EP-2851092-A1 Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170239341-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 LGALS8, SIGLEC7, FUT5 L3MBTL1 2417/4885KMT2A 3584/4885MEN1 2902/4885
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 STT3A, DDOST, LGALS3BP L3MBTL1 2714/4885KMT2A 3980/4885MEN1 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.