Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348165 | 1.00 | FPR2 (0.77) | FPR2POLBALDH1A1NPC1LMNA | |
| SCHEMBL14948919 | 0.87 | FPR2 (1.00) | FPR2POLBALDH1A1NPC1LMNA | |
| SCHEMBL22506221 | 0.87 | FPR2 (1.00) | FPR2POLBALDH1A1NPC1LMNA | |
| SCHEMBL14937931 | 0.87 | FPR2 (1.00) | FPR2POLBALDH1A1NPC1LMNA | |
| SCHEMBL16588668 | 0.84 | FPR2 (0.72) | FPR2POLBALDH1A1LMNARAB9A | |
| SCHEMBL28348638 | 0.84 | FPR2 (0.72) | FPR2POLBALDH1A1LMNARAB9A | |
| SCHEMBL16588635 | 0.84 | FPR2 (0.72) | FPR2POLBALDH1A1LMNARAB9A | |
| SCHEMBL19566147 | 0.82 | FPR2 (0.82) | FPR2POLBALDH1A1NPC1LMNA | |
| SCHEMBL16588717 | 0.82 | FPR2 (0.56) | FPR2ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16588634 | 0.82 | FPR2 (0.56) | FPR2POLBALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240285584-A1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDERECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. | 2024-08-29 | — | — | US | claimed |
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | claimed |
| US-20240285584-A1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDERECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. | 2024-08-29 | — | — | US | disclosed |
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | disclosed |
| US-20150148395-A1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-28 | — | — | US | disclosed |
| US-8993780-B2 | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | ALLERGAN, INC. (US) | 2015-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240285584-A1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDERECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | FPR1, FPR3, FPR2 | FPR2 3/4885POLB 4465/4885ALDH1A1 4067/4885 |
| US-20150148395-A1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | FPR1, FPR3, FPR2 | FPR2 3/4885POLB 4313/4885ALDH1A1 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.