Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588788 | 0.93 | CA1 (0.34) | CA1CA9ALDH1A1KDM4E | |
| SCHEMBL16588652 | 0.92 | CA1 (0.37) | CTRB1CA1CA9ALDH1A1KDM4E | |
| SCHEMBL16588834 | 0.87 | CYP1A2 (0.33) | ALDH1A1HTTKDM4ECYP1A2CYP2C19 | |
| SCHEMBL16588803 | 0.87 | CTRB1 (0.33) | CTRB1HTTTAAR1 | |
| SCHEMBL16588804 | 0.86 | CTRB1 (0.31) | CTRB1CA1CA9 | |
| SCHEMBL16588792 | 0.81 | CA1 (0.35) | CTRB1CA1CA9ALDH1A1 | |
| SCHEMBL16588823 | 0.79 | CYP2D6 (0.38) | ALDH1A1HTTTAAR1KDM4ECYP2C19 | |
| SCHEMBL16588831 | 0.79 | CA1 (0.33) | CA1CA9ALDH1A1KDM4E | |
| SCHEMBL16588808 | 0.78 | MEN1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL16588854 | 0.78 | ALDH1A1 (0.32) | CA1CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |