Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588823 | 0.96 | CYP2D6 (0.38) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16588803 | 0.91 | CTRB1 (0.33) | CYP2D6CYP3A4 | |
| SCHEMBL16588879 | 0.86 | KDM4E (0.33) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL14741940 | 0.85 | KCNA3 (0.39) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16588788 | 0.83 | CA1 (0.34) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16588736 | 0.82 | CRHBP (0.36) | KMT2AKDM4EALDH1A1CYP2D6USP2 | |
| SCHEMBL16588652 | 0.82 | CA1 (0.37) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16588749 | 0.82 | CYP2D6 (0.33) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL14741786 | 0.80 | CYP2D6 (0.38) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16588740 | 0.79 | MEN1 (0.34) | MEN1KMT2AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |