Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588779 | 0.92 | CTRB1 (0.33) | CA1CA9ALDH1A1KDM4ECTRB1 | |
| SCHEMBL16588788 | 0.90 | CA1 (0.34) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL16588854 | 0.87 | ALDH1A1 (0.32) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL16588767 | 0.86 | CA1 (0.35) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL16588803 | 0.84 | CTRB1 (0.33) | CTRB1 | |
| SCHEMBL16588740 | 0.83 | MEN1 (0.34) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL16588823 | 0.83 | CYP2D6 (0.38) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL14741953 | 0.82 | CA1 (0.41) | CA1CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL16588808 | 0.82 | MEN1 (0.35) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16588834 | 0.78 | CYP1A2 (0.33) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |