SCHEMBL1659042

SCHEMBL1659042

CO[SiH2]C1(c2ccc(C)cc2)CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.31
MMP2 P08253 1/20 0.30
HSD11B1 P28845 2/20 0.30
HSD11B2 P80365 2/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356054 0.86 SLC6A4 (0.33)
SCHEMBL5571648 0.77 HSD11B1 (0.32) L3MBTL1HSD11B1HSD11B2
SCHEMBL27610112 0.75 KMT2A (0.37) L3MBTL1MMP2KMT2ASMN1; SMN2
SCHEMBL29035084 0.70 DRD3 (0.35) KMT2ASMN1; SMN2
SCHEMBL43008 0.68 KMT2A (0.34) L3MBTL1HSD11B1HSD11B2KMT2ASMN1; SMN2
SCHEMBL9492152 0.68 SLC6A3 (0.39) HSD11B1
SCHEMBL19466455 0.67 KMT2A (0.33) L3MBTL1HSD11B1HSD11B2KMT2ASMN1; SMN2
SCHEMBL116500 0.67 DPP4 (0.35)
SCHEMBL5650431 0.66 SLC6A2 (0.40) L3MBTL1KMT2ASMN1; SMN2
SCHEMBL27724075 0.66 MMP2 (0.36) MMP2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338511-B2 Thermoplastic polyester resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2012-12-25 US disclosed
EP-2314643-B1 THERMOPLASTIC POLYESTER RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2012-05-16 EP disclosed
US-20110184101-A1 THERMOPLASTIC POLYESTER RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-07-28 US disclosed
EP-2314643-A1 THERMOPLASTIC POLYESTER RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2011-04-27 EP disclosed