Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22809511 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL22809483 | 0.89 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL19664461 | 0.84 | SMN1; SMN2 (0.53) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL13197550 | 0.84 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL22809399 | 0.83 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19SMN1; SMN2RAB9A | |
| SCHEMBL29025473 | 0.83 | SMN1; SMN2 (0.52) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL30433202 | 0.83 | SMN1; SMN2 (0.52) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| SCHEMBL16592086 | 0.83 | SMN1; SMN2 (0.52) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MRGPRX4 | |
| Hydrochloric Acid SCHEMBL28354555 | 0.82 | IDO1 (0.38) | CYP1A2CYP3A4CYP2C19SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL30449797 | 0.82 | IDO1 (0.38) | CYP1A2CYP3A4CYP2C19SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776427-B | Pyrimidine diamine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-23 | — | — | CN | disclosed |
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | RAQUALIA PHARMA INC. (JP) | 2021-10-26 | — | — | US | disclosed |
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-9332754-B2 | Alkyl phenyl sulfide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | SCN8A, SCN7A, SCN1A | CYP1A2 2057/4885CYP3A4 2509/4885CYP2C19 3638/4885 |
| US-20150087833-A1 | ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT | C1S, TRPA1, STK39 | CYP1A2 1244/4885CYP3A4 1870/4885CYP2C19 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.