SCHEMBL16592199

SCHEMBL16592199

COc1ccc(C(=O)Nc2ccc(C(=O)O)c(O)c2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.69
▸ PKM P14618 4/20 0.69
▸ NPC1 O15118 10/20 0.65
▸ RAB9A P51151 10/20 0.65
▸ SMN1; SMN2 Q16637 7/20 0.65
▸ TP53 P04637 6/20 0.65
▸ ALOX15 P16050 1/20 0.65
▸ ALDH1A1 P00352 4/20 0.62
▸ KCNK9 Q9NPC2 1/20 0.62
▸ MAPT P10636 3/20 0.61
▸ MEN1 O00255 4/20 0.60
▸ CYP2C9 P11712 2/20 0.60
▸ CYP1A2 P05177 1/20 0.60
▸ CYP3A4 P08684 1/20 0.60
▸ GAA P10253 1/20 0.60
▸ CYP2D6 P10635 1/20 0.60
▸ CYP2C19 P33261 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.59
▸ SIRT6 Q8N6T7 1/20 0.58
▸ ADORA3 P0DMS8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21242880 0.89 NPC1 (0.65) KMT2APKMNPC1RAB9ASMN1; SMN2
SCHEMBL11592884 0.89 NPC1 (0.69) KMT2APKMNPC1RAB9ASMN1; SMN2
SCHEMBL30772317 0.88 KMT2A (0.87) KMT2APKMALOX15ALDH1A1KCNK9
SCHEMBL27296254 0.88 KMT2A (0.87) KMT2APKMALOX15ALDH1A1KCNK9
SCHEMBL7609498 0.84 KMT2A (0.75) KMT2APKMNPC1RAB9ASMN1; SMN2
SCHEMBL8654945 0.83 KDM4E (0.60) KMT2APKMNPC1RAB9ASMN1; SMN2
SCHEMBL16589419 0.83 NPC1 (0.69) KMT2APKMNPC1RAB9ASMN1; SMN2
SCHEMBL2493877 0.82 SMN1; SMN2 (0.78) KMT2APKMNPC1RAB9ASMN1; SMN2
Benzoylpas SCHEMBL563122 0.82 KMT2A (1.00) KMT2APKMNPC1RAB9AALOX15
SCHEMBL6580095 0.82 NPC1 (0.67) KMT2APKMNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3049387-B1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2020-11-11 — — EP disclosed
EP-3049388-B1 NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & CO (US) 2019-08-07 — — EP disclosed
US-9200144-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-12-01 — — US disclosed
US-9200142-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-12-01 — — US disclosed
US-9193845-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-11-24 — — US disclosed
US-9120914-B2 Thermoplastic polymer composition MILLIKEN & COMPANY (US) 2015-09-01 — — US disclosed
US-20150094406-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2015-04-02 — — US disclosed
WO-2015042565-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2015-03-26 — — WO disclosed
US-20150087758-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2015-03-26 — — US disclosed
WO-2015042563-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2015-03-26 — — WO disclosed
WO-2015042561-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2015-03-26 — — WO disclosed
US-20150087759-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2015-03-26 — — US disclosed
US-20150087757-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2015-03-26 — — US disclosed
WO-2015042562-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2015-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150087757-A1 THERMOPLASTIC POLYMER COMPOSITION PARG, PUF60, MCM7 KMT2A 1047/4885PKM 1861/4885NPC1 1837/4885
US-20150087758-A1 THERMOPLASTIC POLYMER COMPOSITION ERCC4, SMCHD1, XRCC5 KMT2A 1432/4885PKM 1697/4885NPC1 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback