Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.65 |
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592199 | 0.89 | KMT2A (0.69) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL16589419 | 0.83 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6580095 | 0.82 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22640296 | 0.81 | RAB9A (0.86) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL11592884 | 0.80 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.80 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL13086314 | 0.79 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL14184959 | 0.79 | MAPK1 (0.58) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL294143 | 0.78 | CA12 (0.72) | NPC1RAB9ASMN1; SMN2ALOX15ALDH1A1 | |
| SCHEMBL2127575 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049388-B1 | NUCLEATING AGENT FOR THERMOPLASTIC POLYMER COMPOSITION | MILLIKEN & CO (US) | 2019-08-07 | — | — | EP | disclosed |