SCHEMBL165933

SCHEMBL165933

N[C@@H](C=O)[C@@H](OP(=O)(O)O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.36
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
PAX8 Q06710 1/20 0.33
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19948 1.00 MPI (0.36) MPIUSP2SLCO1B1PAX8LMNA
SCHEMBL7155133 1.00 MPI (0.36) MPIUSP2SLCO1B1PAX8LMNA
SCHEMBL181949 1.00 MPI (0.36) MPIUSP2SLCO1B1PAX8LMNA
SCHEMBL10699689 0.88 MPI (0.33) MPIUSP2SLCO1B1PAX8
SCHEMBL9078408 0.88 MPI (0.33) MPIUSP2SLCO1B1PAX8
SCHEMBL705391 0.87 PAX8 (0.36) MPIUSP2SLCO1B1PAX8
SCHEMBL5351083 0.83 ITPR3 (0.31)
SCHEMBL177758 0.83 MPI (0.46) MPILMNAL3MBTL1TDP1
SCHEMBL5972505 0.83 MPI (0.46) MPILMNAL3MBTL1TDP1
SCHEMBL1922060 0.83 MPI (0.46) MPILMNAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293555-A1 CARBOHYDRATE CONJUGATES FOR THE DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES CEDARS-SINAI MEDICAL CENTER 2024-09-05 US disclosed
WO-2012027797-A1 ANTI-INFLAMMATORY COMPOSTION JAMES DAVID CHARLES (AU) 2012-03-08 WO disclosed
EP-0653438-A2 Oligonucleotide compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293555-A1 CARBOHYDRATE CONJUGATES FOR THE DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES CSGALNACT1, SLC2A8, FUT6 MPI 38/4885USP2 3383/4885SLCO1B1 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.