SCHEMBL165934

SCHEMBL165934

N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)COP(=O)(O)O

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.59
PGD P52209 3/20 0.49
PGK1 P00558 1/20 0.44
PGK2 P07205 1/20 0.44
S1PR1 P21453 3/20 0.36
S1PR3 Q99500 3/20 0.36
S1PR5 Q9H228 3/20 0.36
S1PR4 O95977 2/20 0.36
S1PR2 O95136 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TSPO P30536 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2849450 1.00 MPI (0.59) MPIPGDPGK1PGK2S1PR1
SCHEMBL19393 1.00 MPI (0.59) MPIPGDPGK1PGK2S1PR1
SCHEMBL158926 1.00 MPI (0.59) MPIPGDPGK1PGK2S1PR1
SCHEMBL20718807 1.00 MPI (0.59) MPIPGDPGK1PGK2S1PR1
SCHEMBL23787745 0.89 MPI (0.49) MPIPGDPGK1PGK2S1PR1
SCHEMBL9078417 0.87 MPI (0.45) MPIPGD
SCHEMBL2851628 0.86 MPI (0.43) MPIPGDPGK1PGK2
SCHEMBL2851632 0.84 MPI (0.41) MPIPGD
SCHEMBL9937657 0.84 MPI (0.49) MPIPGDPGK1PGK2S1PR1
SCHEMBL2851638 0.84 MPI (0.41) MPIPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006006757-A1 COMPOSITION FOR LOWERING BLOOD GLUCOSE COMPRISING HEXOSE MONOPHOSPHATE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2006-01-19 WO claimed
US-20240293555-A1 CARBOHYDRATE CONJUGATES FOR THE DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES CEDARS-SINAI MEDICAL CENTER 2024-09-05 US disclosed
WO-2012027797-A1 ANTI-INFLAMMATORY COMPOSTION JAMES DAVID CHARLES (AU) 2012-03-08 WO disclosed
US-20110099668-A1 Expressing GLK in plants HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF AGRICULTURE AND AGRI-FOOD (CA) 2011-04-28 US disclosed
US-20100324123-A1 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES YALE UNIVERSITY (US) 2010-12-23 US disclosed
EP-2061480-A2 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES YALE UNIVERSITY (US) 2009-05-27 EP disclosed
WO-2008076156-A2 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES YALE UNIVERSITY (US) 2008-06-26 WO disclosed
EP-1887081-A2 DNA Sequences Ceres Incorporated (US) 2008-02-13 EP disclosed
WO-2006006757-A1 COMPOSITION FOR LOWERING BLOOD GLUCOSE COMPRISING HEXOSE MONOPHOSPHATE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2006-01-19 WO disclosed
EP-1586645-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2005-10-19 EP disclosed
US-20020061301-A1 HUMAN CARBOHYDRATE METABOLISM ENZYMES INCYTE PHARMACEUTICALS, INC. 2002-05-23 US disclosed
EP-1059354-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-12-13 EP disclosed
EP-1033405-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-09-06 EP disclosed
EP-0653438-A2 Oligonucleotide compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293555-A1 CARBOHYDRATE CONJUGATES FOR THE DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES CSGALNACT1, SLC2A8, FUT6 MPI 38/4885PGD 793/4885PGK1 1183/4885
US-20100324123-A1 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES GLMN, RNGTT, GMPS MPI 1155/4885PGD 371/4885PGK1 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.