Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | PGD | P52209 | 3/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165934 | 0.84 | MPI (0.59) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL20718807 | 0.84 | MPI (0.59) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL158926 | 0.84 | MPI (0.59) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL19393 | 0.84 | MPI (0.59) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL2849450 | 0.84 | MPI (0.59) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL1300480 | 0.82 | MPI (0.56) | MPIPGDPGK1PGK2S1PR4 | |
| SCHEMBL16416132 | 0.81 | PGD (0.61) | MPIPGDPGK1PGK2 | |
| SCHEMBL5000804 | 0.81 | PGD (0.61) | MPIPGDPGK1PGK2 | |
| SCHEMBL2859324 | 0.76 | MPI (0.49) | MPIPGDPGK1PGK2LPAR2 | |
| SCHEMBL2853495 | 0.76 | PGD (0.55) | MPIPGDPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846645-B2 | Cyclohexane compounds and their use as antibiotics | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20140066409-A1 | CYCLOHEXANE COMPOUNDS AND THEIR USE AS ANTIBIOTICS | Universität Konstanz (DE) | 2014-03-06 | — | — | US | disclosed |
| EP-2651878-A1 | CYCLOHEXANE COMPOUNDS AND THEIR USE AS ANTIBIOTICS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2489654-A1 | Cyclohexane compounds and their use as antibiotics | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012080240-A1 | CYCLOHEXANE COMPOUNDS AND THEIR USE AS ANTIBIOTICS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN (DE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066409-A1 | CYCLOHEXANE COMPOUNDS AND THEIR USE AS ANTIBIOTICS | NISCH, DCXR, CFTR | MPI 849/4885PGD 89/4885PGK1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.