Cyclohexane

Cyclohexane

SCHEMBL1659384

C1CCCCC1.CC(=O)OC(C)C

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.82
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM1 P11229 1/20 0.41
TBXA2R P21731 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
GALR3 O60755 1/20 0.39
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
HCAR2 Q8TDS4 1/20 0.37
ALDH1A1 P00352 2/20 0.35
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA9 Q16790 4/20 0.33
CA7 P43166 3/20 0.33
CA14 Q9ULX7 3/20 0.33
LMNA P02545 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL6963396 1.00 TSHR (0.82) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL21064874 0.91 TSHR (1.00) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL19193 0.91
Hydrochloric Acid SCHEMBL2107550 0.88
SCHEMBL4431010 0.88 TSHR (0.93) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL3495565 0.88
Methyl Alcohol SCHEMBL584909 0.88
SCHEMBL1278490 0.88
Ammonia Solution, Strong SCHEMBL5086843 0.88
Water SCHEMBL1289230 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754975-B1 Process of reducing trace levels of metal impurities from resist components OLIN CORP (US) 1999-09-01 EP claimed
US-5618655-A Process of reducing trace levels of metal impurities from resist components OLIN CORPORATION (US) 1997-04-08 US claimed
EP-0754975-A2 Process of reducing trace levels of metal impurities from resist components OLIN CORPORATION (US) 1997-01-22 EP claimed
JP-9034127-A None JP disclosed
CN-119591813-A Polyamide-s-triazine polymer, preparation method thereof and solid lubrication composite material 季华实验室 2025-03-11 CN disclosed
US-20240239746-A1 PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND SUNSHINE LAKE PHARMA CO., LTD. (CN) 2024-07-18 US disclosed
EP-3727327-B1 USE OF MAGNOLIA ABSOLUTE IN COSMETICS FOR DEPIGMENTING THE SKIN ROBERTET SA (FR) 2024-05-15 EP disclosed
CN-115246785-B Process for preparing pyrrole amide compounds 年衍药业(珠海)有限公司 2024-03-26 CN disclosed
EP-4332091-A1 PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND Sunshine Lake Pharma Co., Ltd. (CN) 2024-03-06 EP disclosed
US-20230301974-A1 PROCESSES OF MAKING AND CRYSTALLINE FORMS OF A MDM2 INHIBITOR AMGEN INC. (US) 2023-09-28 US disclosed
EP-4245299-A2 Pharmaceutical formulations containing dapagliflozin propylene glycol hydrate Astrazeneca AB (SE) 2023-09-20 EP disclosed
EP-0596067-A1 ESSENTIAL OIL. GIVAUDAN ROURE INT (CH) 1994-05-11 EP disclosed
WO-1993023509-A1 ESSENTIAL OIL GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) 1993-11-25 WO disclosed
US-5134135-A Antiandrogenic sulfonylsteroidooxazoles STERLING DRUG INC. (US) 1992-07-28 US disclosed
US-4816470-A Heterocyclic compounds GLAXO GROUP LIMITED 1989-03-28 US disclosed
US-4795756-A VASOCONSTRICTOR FOR MIGRAINE HEADACHE GLAXO GROUP LIMITED (GB) 1989-01-03 US disclosed
EP-0244085-A2 3-(2-Aminoethyl)indole derivatives GLAXO GROUP LIMITED (GB) 1987-11-04 EP disclosed
US-4025551-A 3-Amino-N-substituted succinamic acids G. D. SEARLE & CO. (US) 1977-05-24 US disclosed
US-4011260-A 3-AMINO-N-SUBSTITUTED SUCCINAMIC ACIDS AND INTERMEDIATES THERETO G. D. SEARLE & CO. (US) 1977-03-08 US disclosed
JP-H00934127-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239746-A1 PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND HPGDS, HRH4, FAAH TSHR 794/4885CHRM2 1763/4885CHRM4 1644/4885
US-20230301974-A1 PROCESSES OF MAKING AND CRYSTALLINE FORMS OF A MDM2 INHIBITOR MDM2, TP53, TP53BP1 TSHR 3716/4885CHRM2 3092/4885CHRM4 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.