Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970702 | 1.00 | KMT2A (0.42) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL14970638 | 0.84 | ALDH1A1 (0.38) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL16596981 | 0.84 | ALDH1A1 (0.38) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL14966026 | 0.83 | MEN1 (0.39) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL16596969 | 0.83 | MEN1 (0.39) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL14968879 | 0.83 | MEN1 (0.39) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL24297214 | 0.80 | ALDH1A1 (0.36) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL16596970 | 0.79 | MEN1 (0.37) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL14969012 | 0.79 | MEN1 (0.37) | KMT2AMEN1GAAAMY1APOLB | |
| SCHEMBL31415058 | 0.79 | MEN1 (0.37) | KMT2AMEN1GAAAMY1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9440927-B2 | Process for preparation of substituted 3'-hydroazino-diphenyl-3-carboxylic acid compounds | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-09-13 | — | — | US | disclosed |
| US-20150087845-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDROAZINO-DIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | GLENMARK GENERICS LIMITED (IN) | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087845-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDROAZINO-DIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | CYP3A5, UGT1A3, HPD | KMT2A 702/4885MEN1 3749/4885GAA 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.