Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.39 |
| ▸ | ITGAV | P06756 | 10/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113683 | 0.83 | CTSC (0.47) | CTSCKMT2A | |
| SCHEMBL3113689 | 0.83 | CTSC (0.47) | CTSCKMT2A | |
| SCHEMBL16598553 | 0.82 | ROCK2 (0.37) | ITGB1ITGAVITGA5CTSCITGB3 | |
| SCHEMBL16598457 | 0.82 | ITGB1 (0.35) | ITGB1ITGAVITGA5CTSCITGB3 | |
| SCHEMBL19412232 | 0.77 | CTSC (0.39) | CTSCMEN1KMT2A | |
| SCHEMBL19412130 | 0.75 | CTSC (0.37) | ITGB1ITGA5CTSCITGB3ITGA2B | |
| SCHEMBL27565204 | 0.74 | CTSC (0.47) | CTSC | |
| SCHEMBL19412214 | 0.73 | CTSC (0.37) | CTSCITGB3ITGA2BTERT | |
| SCHEMBL7450270 | 0.73 | BCHE (0.47) | CTSCSMN1; SMN2 | |
| SCHEMBL6429094 | 0.73 | CTSC (0.37) | CTSCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052515-A1 | ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS | The Regents of the University of California (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015048819-A1 | ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-02 | — | — | WO | disclosed |