Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635684 | 0.89 | CTSL (0.45) | CARM1PRMT6MEN1KMT2ACYP2C19 | |
| SCHEMBL1560842 | 0.89 | CTSL (0.45) | CARM1PRMT6MEN1KMT2ACYP2C19 | |
| SCHEMBL11637675 | 0.89 | CTSL (0.45) | CARM1PRMT6MEN1KMT2ACYP2C19 | |
| SCHEMBL11632428 | 0.85 | NAAA (0.42) | MEN1KMT2ACYP2C19CTSLCTSB | |
| SCHEMBL11634473 | 0.85 | MEN1 (0.42) | KDM1ACARM1PRMT6MEN1KMT2A | |
| SCHEMBL11634478 | 0.85 | MEN1 (0.42) | KDM1ACARM1PRMT6MEN1KMT2A | |
| SCHEMBL11633899 | 0.85 | SLC18A3 (0.48) | FABP7FABP5KDM1ACARM1PRMT6 | |
| SCHEMBL17434601 | 0.85 | APP (0.42) | MEN1KMT2ACYP2C19CTSLCTSB | |
| SCHEMBL11633902 | 0.85 | SLC18A3 (0.48) | FABP7FABP5KDM1ACARM1PRMT6 | |
| SCHEMBL11632425 | 0.85 | NAAA (0.42) | MEN1KMT2ACYP2C19CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244436-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITING CYTOCHROME P450 INHIBITION AND THEIR METHOD OF USE | CORTENDO AB (PUBL) | 2016-08-25 | — | — | US | disclosed |
| US-20160244436-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITING CYTOCHROME P450 INHIBITION AND THEIR METHOD OF USE | CORTENDO AB (PUBL) | 2016-08-25 | — | — | US | disclosed |
| US-20160244436-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITING CYTOCHROME P450 INHIBITION AND THEIR METHOD OF USE | CORTENDO AB (PUBL) | 2016-08-25 | — | — | US | disclosed |
| EP-3049084-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITNG CYTOCHROME P450 INHIBITION | Cortendo AB (publ) (US) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015048311-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITNG CYTOCHROME P450 INHIBITION | CORTENDO AB (PUBL) (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015048311-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITNG CYTOCHROME P450 INHIBITION | CORTENDO AB (PUBL) (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244436-A1 | NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITING CYTOCHROME P450 INHIBITION AND THEIR METHOD OF USE | CYP11B1, CYP11B2, CYP21A2 | FABP7 370/4885FABP5 860/4885KDM1A 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.