Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398852 | 0.86 | APP (0.58) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL19133572 | 0.83 | APP (0.57) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL27989389 | 0.83 | APP (0.57) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL21870995 | 0.83 | APP (0.50) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL21052187 | 0.83 | APP (0.50) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL21999866 | 0.83 | APP (0.50) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL23681856 | 0.81 | APP (0.57) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL12854022 | 0.81 | APP (0.55) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL845603 | 0.80 | APP (0.63) | APPCA2CA1CA9CYP2A6 | |
| SCHEMBL29732980 | 0.80 | APP (0.63) | APPCA2CA1CA9CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | FLEXENABLE LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | FLEXENABLE LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| EP-3052506-B1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | FLEXENABLE LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| EP-3052506-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015043722-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015043722-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | AZI2, NME2, ALKBH2 | APP 4264/4885CA2 4607/4885CA1 4716/4885 |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | AZI2, NME2, ALKBH2 | APP 4264/4885CA2 4607/4885CA1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.