Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | BLM | P54132 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805943 | 0.88 | GAA (0.44) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL7808886 | 0.88 | MAPK1 (0.41) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL7807450 | 0.83 | TAAR1 (0.53) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL6873928 | 0.83 | TAAR1 (0.53) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL19199419 | 0.81 | ADORA2A (0.49) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL22897894 | 0.81 | ADORA2A (0.49) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| Hydrochloric Acid SCHEMBL7807700 | 0.81 | TAAR1 (0.52) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL8586029 | 0.80 | ADORA2A (0.48) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL397270 | 0.79 | ALDH1A1 (0.52) | TAAR1ALDH1A1MAPTBLMKDM4E | |
| SCHEMBL29634306 | 0.79 | ALDH1A1 (0.52) | TAAR1ALDH1A1MAPTBLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | FLEXENABLE LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | FLEXENABLE LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| EP-3052506-B1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | FLEXENABLE LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| EP-3052506-B1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | FLEXENABLE LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| EP-3052506-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015043722-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015043722-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10840460-B2 | Azaborinine derivatives, their synthesis and use in organic electronic devices | AZI2, NME2, ALKBH2 | TAAR1 1053/4885ALDH1A1 450/4885MAPT 1747/4885 |
| US-20160248014-A1 | AZABORININE DERIVATIVES, THEIR SYNTHESIS AND USE IN ORGANIC ELECTRONIC DEVICES | AZI2, NME2, ALKBH2 | TAAR1 1053/4885ALDH1A1 450/4885MAPT 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.