Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671945 | 0.90 | ENPP2 (0.42) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16614261 | 0.88 | ENPP2 (0.49) | ENPP2 | |
| SCHEMBL16600363 | 0.82 | L3MBTL1 (0.46) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16600182 | 0.81 | ENPP2 (0.42) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16600389 | 0.79 | ENPP2 (0.50) | ENPP2NR4A2MRGPRX4ALDH1A1MAPT | |
| SCHEMBL671979 | 0.78 | ENPP2 (0.36) | ENPP2MAPT | |
| SCHEMBL16600575 | 0.77 | ENPP2 (0.48) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30147027 | 0.77 | ENPP2 (0.48) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL671757 | 0.72 | ENPP2 (0.51) | ENPP2PDE3BPDE3A | |
| SCHEMBL672285 | 0.72 | ENPP2 (0.56) | ENPP2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |