Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600623 | 0.88 | ENPP2 (0.42) | ENPP2 | |
| SCHEMBL671945 | 0.86 | ENPP2 (0.42) | ENPP2 | |
| SCHEMBL16600621 | 0.83 | CLCN2 (0.44) | ENPP2GPR17NOTUMADRA2ACLCN2 | |
| SCHEMBL16601100 | 0.83 | ENPP2 (0.53) | ENPP2GPR17NOTUM | |
| SCHEMBL16600515 | 0.79 | ENPP2 (0.64) | ENPP2 | |
| SCHEMBL671979 | 0.78 | ENPP2 (0.36) | ENPP2GPR17 | |
| SCHEMBL16600182 | 0.78 | ENPP2 (0.42) | ENPP2 | |
| SCHEMBL16600363 | 0.75 | L3MBTL1 (0.46) | ENPP2GPR17 | |
| SCHEMBL16600573 | 0.73 | ENPP2 (0.39) | ENPP2 | |
| SCHEMBL14668202 | 0.73 | ENPP2 (0.53) | ENPP2GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |