Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601159 | 0.83 | GRIN2B (0.60) | GRIN2BGRIN1 | |
| SCHEMBL16601003 | 0.83 | GRIN2B (0.60) | GRIN2BGRIN1 | |
| SCHEMBL16601043 | 0.78 | GRIN2B (0.66) | GRIN2BGRIN1 | |
| SCHEMBL16601492 | 0.78 | GRIN2B (0.66) | GRIN2BGRIN1 | |
| SCHEMBL16608162 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16601007 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16601009 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL16601008 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL18622657 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL5732849 | 0.74 | GRIN2B (0.40) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036221-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Luc Therapeutics, Inc. (US) | 2016-06-29 | — | — | EP | claimed |
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | claimed |
| EP-3036221-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Luc Therapeutics, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |