Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601003 | 0.83 | GRIN2B (0.60) | GRIN2BCYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL16601159 | 0.83 | GRIN2B (0.60) | GRIN2BCYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL583721 | 0.76 | CYP1A2 (0.58) | MEN1KMT2AIDO1CYP1A2CYP3A4 | |
| SCHEMBL7987714 | 0.75 | IDO1 (0.39) | GRIN2BMEN1KMT2ADPP4IDO1 | |
| Hydrochloric Acid SCHEMBL8017800 | 0.74 | CYP1A2 (0.56) | MEN1KMT2AIDO1CYP1A2CYP3A4 | |
| SCHEMBL6064058 | 0.74 | CYP1A2 (0.61) | KMT2AIDO1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10454919 | 0.71 | KCNA5 (0.49) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL4131831 | 0.71 | SLC6A4 (0.63) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22875083 | 0.70 | LMNA (0.46) | GRIN2BMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12372536 | 0.67 | FUCA1 (0.60) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615634-A1 | SUBSTITUTED AZABICYCLO HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES, LTD. (IN) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089363-A1 | SUBSTITUTED AZABICYCLO HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-10-21 | — | — | WO | disclosed |