Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895069 | 0.82 | CYP2D6 (0.54) | HSD11B1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL6318888 | 0.82 | S1PR5 (0.53) | HSD11B1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL6733582 | 0.81 | CYP3A4 (0.46) | HSD11B1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL2955795 | 0.78 | FUCA1 (0.60) | S1PR5S1PR1ALDH1A1FUCA1 | |
| SCHEMBL6732909 | 0.76 | KDM4E (0.50) | HSD11B1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL9269370 | 0.76 | KMT2A (0.48) | S1PR5S1PR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6737613 | 0.76 | FAAH (0.66) | — | |
| SCHEMBL584913 | 0.75 | JAK2 (0.48) | HSD11B1S1PR5S1PR1KMT2AL3MBTL1 | |
| SCHEMBL9520441 | 0.75 | CYP2C9 (0.53) | HSD11B1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL9521948 | 0.75 | ALDH1A1 (0.50) | S1PR5S1PR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052498-A1 | 3,7-DIAZABICYCLO[3.3.1]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | Council of Scientific & Industrial Research (IN) | 2016-08-10 | — | — | EP | claimed |
| WO-2015044951-A1 | 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-02 | — | — | WO | claimed |