Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 16/20 | 1.00 |
| ▸ | NPC1 | O15118 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13238168 | 0.91 | SMN1; SMN2 (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL19627009 | 0.84 | RAB9A (0.72) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12895744 | 0.84 | RAB9A (0.72) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7238213 | 0.83 | RAB9A (0.97) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12987199 | 0.81 | RAB9A (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13341087 | 0.81 | RAB9A (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12923168 | 0.81 | RAB9A (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL17702004 | 0.79 | RAB9A (0.66) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12297233 | 0.77 | RAB9A (0.83) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12297528 | 0.76 | SMN1; SMN2 (0.93) | RAB9ANPC1ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| US-9096518-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-8993585-B2 | Cyclic amine substituted pyrimidinediamines as PKC inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC5, HDAC1 | RAB9A 2715/4885NPC1 1972/4885ALDH1A1 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.