Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 18/20 | 0.66 |
| ▸ | NPC1 | O15118 | 16/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12923168 | 0.86 | RAB9A (0.68) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12895744 | 0.81 | RAB9A (0.72) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16601588 | 0.79 | RAB9A (1.00) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7238213 | 0.77 | RAB9A (0.97) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13341087 | 0.75 | RAB9A (0.68) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12775984 | 0.74 | L3MBTL1 (0.59) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13021195 | 0.74 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12775955 | 0.74 | RAB9A (0.59) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12297233 | 0.72 | RAB9A (0.83) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12775950 | 0.70 | KDM4E (0.59) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321731-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-04-26 | — | — | US | disclosed |