SCHEMBL16601614

SCHEMBL16601614

CN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1c(F)c(F)c(F)c(F)c1F)C3=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
ALDH1A1 P00352 6/20 0.41
HPGD P15428 4/20 0.41
KDM4E B2RXH2 3/20 0.41
USP2 O75604 2/20 0.41
KEAP1 Q14145 2/20 0.41
NFE2L2 Q16236 2/20 0.41
ATM Q13315 1/20 0.41
POLB P06746 4/20 0.41
HSD17B10 Q99714 4/20 0.41
PRMT1 Q99873 1/20 0.39
APAF1 O14727 1/20 0.39
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
MAPK1 P28482 1/20 0.38
CASP3 P42574 1/20 0.37
TERT O14746 3/20 0.37
ALOX15 P16050 2/20 0.37
PTPN7 P35236 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12347165 0.90 POLB (0.45) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL24453229 0.86 MEN1 (0.47) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL2222018 0.83 TERT (0.41) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL13577705 0.81 POLB (0.39) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL20742730 0.80 TYMS (0.38) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL30937815 0.79 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL127059 0.79 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL14268824 0.79 TERT (0.38) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL14922759 0.77 DPP4 (0.38) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL12347156 0.77 POLB (0.41) MEN1KMT2AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed