Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12108041 | 0.94 | DPP4 (0.38) | DPP4ANPEPGRM1GRM7GRM4 | |
| SCHEMBL12347165 | 0.82 | POLB (0.45) | DPP4ANPEPPOLBAPAF1NPC1 | |
| SCHEMBL16676004 | 0.77 | DPP4 (0.56) | DPP4ANPEPNPC1RAB9AMEN1 | |
| SCHEMBL16601614 | 0.77 | MEN1 (0.41) | POLBAPAF1NPC1RAB9AMEN1 | |
| SCHEMBL13577705 | 0.77 | POLB (0.39) | DPP4ANPEPGRM1POLBAPAF1 | |
| SCHEMBL2222018 | 0.75 | TERT (0.41) | POLBAPAF1NPC1RAB9AMEN1 | |
| SCHEMBL14268824 | 0.74 | TERT (0.38) | DPP4ANPEPPOLBAPAF1NPC1 | |
| SCHEMBL13578762 | 0.74 | GRM1 (0.33) | GRM1GRM7GRM4MEN1KMT2A | |
| SCHEMBL13784274 | 0.74 | APAF1 (0.34) | POLBAPAF1NPC1RAB9A | |
| SCHEMBL19009044 | 0.74 | MEN1 (0.41) | POLBMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |