SCHEMBL2222018

SCHEMBL2222018

O=C1c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C(=O)N1c1c(F)c(F)c(F)c(F)c1F)c64)C(=O)N(c1c(F)c(F)c(F)c(F)c1F)C5=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 4/20 0.41
POLB P06746 3/20 0.40
APAF1 O14727 1/20 0.40
STAT3 P40763 1/20 0.39
HIF1A Q16665 1/20 0.39
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
BCL2 P10415 1/20 0.33
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
USP2 O75604 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KEAP1 Q14145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14268824 0.95 TERT (0.38) TERTPOLBAPAF1STAT3HIF1A
SCHEMBL12347165 0.92 POLB (0.45) TERTPOLBAPAF1NPC1RAB9A
SCHEMBL12347175 0.87 TERT (0.38) TERTPOLBAPAF1STAT3HIF1A
SCHEMBL13784275 0.85 TERT (0.35) TERTPOLBAPAF1STAT3HIF1A
SCHEMBL14268814 0.84 TERT (0.38) TERTPOLBAPAF1STAT3HIF1A
SCHEMBL13784274 0.83 APAF1 (0.34) TERTPOLBAPAF1NPC1RAB9A
SCHEMBL13577705 0.83 POLB (0.39) POLBAPAF1NPC1RAB9ACA12
SCHEMBL16601614 0.83 MEN1 (0.41) TERTPOLBAPAF1NPC1RAB9A
SCHEMBL13259577 0.83 APAF1 (0.32) TERTPOLBAPAF1
SCHEMBL20742730 0.81 TYMS (0.38) POLBAPAF1NPC1RAB9ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140155603-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2014-06-05 US disclosed
US-20140155603-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2014-06-05 US disclosed
US-8674104-B2 Halogen-containing perylenetetracarboxylic acid derivatives and the use thereof BASF SE (DE) 2014-03-18 US disclosed
US-8674104-B2 Halogen-containing perylenetetracarboxylic acid derivatives and the use thereof BASF SE (DE) 2014-03-18 US disclosed
US-8481999-B2 Hydrogen penetration barrier KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE (KR) 2013-07-09 US disclosed
US-20130123495-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF CLAP CO., LTD. (KR) 2013-05-16 US disclosed
US-20130123495-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF CLAP CO., LTD. (KR) 2013-05-16 US disclosed
EP-2355198-A1 OLED electron-injecting layer Global OLED Technology LLC (US) 2011-08-10 EP disclosed
US-20110175078-A1 HYDROGEN PENETRATION BARRIER KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE (KR) 2011-07-21 US disclosed
US-20110068328-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2011-03-24 US disclosed
US-20110068328-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2011-03-24 US disclosed
WO-2010032944-A2 MEMBRANE FOR PREVENTING HYDROGEN PERMEATION 한국표준과학연구원 (KR) 2010-03-25 WO disclosed
US-7629741-B2 OLED electron-injecting layer EASTMAN KODAK COMPANY (US) 2009-12-08 US disclosed
US-7629741-B2 OLED electron-injecting layer EASTMAN KODAK COMPANY (US) 2009-12-08 US disclosed
WO-2009024512-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2009-02-26 WO disclosed
US-7326956-B2 Fluorine-containing N,N′-diaryl perylene-based tetracarboxylic diimide compounds as N-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2008-02-05 US disclosed
US-7326956-B2 Fluorine-containing N,N′-diaryl perylene-based tetracarboxylic diimide compounds as N-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2008-02-05 US disclosed
WO-2007130047-A1 OLED ELECTRON-INJECTING LAYER EASTMAN KODAK COMPANY (US) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110068328-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF NR0B1, NR0B2, RXRB TERT 2973/4885POLB 1482/4885APAF1 4157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.