Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.54 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601618 | 0.79 | CA12 (0.54) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16602016 | 0.78 | MAP4K4 (0.56) | AXLFYNSYK | |
| SCHEMBL16601622 | 0.78 | KMT2A (0.48) | KMT2AFYNALDH1A1 | |
| SCHEMBL1950804 | 0.76 | CDK8 (0.56) | CDK8NEK1AXLGABRG2GABRB3 | |
| SCHEMBL5562440 | 0.74 | CDK8 (0.60) | CDK8NEK1AXLGABRG2GABRB3 | |
| SCHEMBL410498 | 0.74 | GABRG2 (0.54) | CDK8NEK1AXLGABRG2GABRB3 | |
| SCHEMBL67941 | 0.74 | CA12 (0.68) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16656189 | 0.73 | KMT2A (0.54) | KMT2AFYNALDH1A1 | |
| SCHEMBL7719381 | 0.73 | CA12 (0.59) | CDK8GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30285148 | 0.73 | CA12 (0.59) | CDK8GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |