SCHEMBL16601658

SCHEMBL16601658

CC(C)CC(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCOCCO)C3=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
HTT P42858 2/20 0.43
KMT2A Q03164 2/20 0.43
RGS12 O14924 1/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
PABPC1 P11940 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TERT O14746 7/20 0.38
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TLR9 Q9NR96 1/20 0.35
PIN1 Q13526 1/20 0.35
PIN4 Q9Y237 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656205 0.90 ALDH1A1 (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL15764205 0.89 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL15764213 0.83 ALDH1A1 (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL18080686 0.83 KDM4E (0.61) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL16656196 0.82 KDM4E (0.64) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL15764209 0.81 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL18351303 0.81 ALDH1A1 (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL18080688 0.79 KDM4E (0.53) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL16656202 0.79 TERT (0.53) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL21226293 0.77 TERT (0.42) KDM4EALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed