SCHEMBL16656205

SCHEMBL16656205

CCOCCN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(CO)CC(C)C)C3=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
RGS12 O14924 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
PABPC1 P11940 1/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PIN1 Q13526 1/20 0.40
PIN4 Q9Y237 1/20 0.40
TERT O14746 7/20 0.38
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
TLR9 Q9NR96 1/20 0.35
STAT3 P40763 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601658 0.90 KDM4E (0.43) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL15764213 0.83 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL15764205 0.81 KDM4E (0.44) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL18351303 0.81 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL21477330 0.81 TERT (0.53) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL15672179 0.81 TERT (0.42) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL16656196 0.80 KDM4E (0.64) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL15764209 0.79 KDM4E (0.44) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL21226293 0.77 TERT (0.42) ALDH1A1KDM4EMEN1RGS12NPC1
SCHEMBL16656194 0.77 TERT (0.49) ALDH1A1KDM4EMEN1RGS12NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed