SCHEMBL16601680

SCHEMBL16601680

CC(C)C(CO)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(CO)C(C)C)C3=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
RECQL P46063 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
RGS12 O14924 1/20 0.41
PABPC1 P11940 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TERT O14746 6/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PIN1 Q13526 1/20 0.37
PIN4 Q9Y237 1/20 0.37
GAA P10253 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
APAF1 O14727 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30630019 0.85 LMNA (0.53) LMNAKDM4EHTTNPC1ALDH1A1
SCHEMBL31671417 0.85 LMNA (0.53) LMNAKDM4EHTTNPC1ALDH1A1
SCHEMBL820702 0.85 LMNA (0.53) LMNAKDM4EHTTNPC1ALDH1A1
SCHEMBL13669517 0.85 LMNA (0.53) LMNAKDM4EHTTNPC1ALDH1A1
SCHEMBL10262386 0.85 LMNA (0.54) LMNAKDM4EHTTKMT2AALDH1A1
SCHEMBL16601679 0.84 KDM4E (0.38) LMNAKDM4EHTTNPC1RAB9A
SCHEMBL16866429 0.82 POLB (0.43) KDM4ENPC1RAB9AKMT2AALDH1A1
SCHEMBL10261546 0.81 ALDH1A1 (0.57) LMNAKDM4EHTTNPC1RAB9A
SCHEMBL10261835 0.81 CYP1B1 (0.57) LMNAKDM4ENPC1KMT2AALDH1A1
SCHEMBL21226292 0.79 TERT (0.40) LMNAKDM4EHTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed