SCHEMBL16601708

SCHEMBL16601708

CCc1cccc(CC)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1CCO)C3=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.52
DPP4 P27487 2/20 0.52
NR1H3 Q13133 4/20 0.49
NR1H2 P55055 3/20 0.49
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
MGLL Q99685 1/20 0.42
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 3/20 0.41
USP2 O75604 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
CASP1 P29466 1/20 0.41
BRCA1 P38398 1/20 0.41
CASP7 P55210 1/20 0.41
HBB P68871 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601810 0.95 ANPEP (0.48) ANPEPDPP4NR1H3NR1H2CRHBP
SCHEMBL12556946 0.89 ANPEP (0.55) ANPEPDPP4NR1H3NR1H2CRHBP
SCHEMBL16601691 0.89 NR1H3 (0.55) NR1H3NR1H2CRHBPCRHR2MGLL
SCHEMBL16601811 0.85 ANPEP (0.50) ANPEPDPP4NR1H3NR1H2CRHBP
SCHEMBL16601840 0.84 ANPEP (0.41) ANPEPDPP4NR1H3NR1H2CRHBP
SCHEMBL16601772 0.83 NR1H3 (0.50) NR1H3NR1H2CRHBPCRHR2MEN1
SCHEMBL22221562 0.83 ANPEP (0.66) ANPEPDPP4CRHBPCRHR2MGLL
SCHEMBL17263572 0.82 MEN1 (0.52) ANPEPDPP4NR1H3NR1H2CRHBP
SCHEMBL1904159 0.80 NR1H3 (0.68) NR1H3NR1H2MGLLALDH1A1CASP1
SCHEMBL16601608 0.77 ANPEP (0.59) ANPEPDPP4CRHBPCRHR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed