Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | NAT1 | P18440 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17715426 | 0.86 | NAT1 (0.38) | DHODHS100A4CDC25ACDC25BPRKCI | |
| SCHEMBL9695242 | 0.76 | MAPT (0.61) | S100A4CDC25ACDC25BHSP90AA1HSP90AB1 | |
| SCHEMBL15764211 | 0.75 | NPC1 (0.64) | DHODHS100A4PRKCICNR2MAPT | |
| SCHEMBL10981826 | 0.74 | HTR7 (0.65) | PRKCIPDCD1CD274 | |
| SCHEMBL16601788 | 0.73 | BACE1 (0.60) | DHODHS100A4CDC25ACDC25BPRKCI | |
| SCHEMBL15498628 | 0.73 | PRKCI (0.55) | PRKCICNR2ACMSDPDCD1CD274 | |
| SCHEMBL1556617 | 0.72 | CDC25B (0.60) | S100A4CDC25ACDC25BMAPTLMNA | |
| SCHEMBL23479734 | 0.70 | FFAR1 (0.52) | PRKCI | |
| SCHEMBL4191589 | 0.70 | PRKCI (0.72) | PRKCICNR2ACMSD | |
| SCHEMBL6027623 | 0.69 | HTR7 (0.50) | PRKCIACMSDPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |