SCHEMBL16601775

SCHEMBL16601775

O=C1c2cc(-c3ccc(O)cc3)ccc2C(=O)c2c(CCO)cccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.41
ESR1 P03372 4/20 0.40
ESR2 Q92731 3/20 0.40
MAOB P27338 2/20 0.40
MAOA P21397 2/20 0.40
UGT1A1 P22309 1/20 0.40
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
PABPC1 P11940 1/20 0.39
MAPT P10636 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
LMNA P02545 2/20 0.39
THRB P10828 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
APAF1 O14727 1/20 0.39
XBP1 P17861 1/20 0.39
PTBP1 P26599 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601839 0.86 BACE1 (0.43) MAOBMAOAMEN1KMT2APABPC1
SCHEMBL16601842 0.84 TTR (0.49) TTRESR1ESR2MAOBMAOA
SCHEMBL2316204 0.81 MEN1 (0.54) MAOBMAOAMEN1KMT2APABPC1
SCHEMBL2308920 0.81 MAPT (0.45) TTRMAOBMAOAMEN1KMT2A
SCHEMBL2310241 0.81 MAPT (0.45) TTRMAOBMAOAMEN1KMT2A
SCHEMBL16656217 0.80 TTR (0.60) TTRESR1ESR2MAOBMAOA
SCHEMBL2313485 0.80 MAOA (0.48) MAOBMAOAMEN1KMT2APABPC1
SCHEMBL2311538 0.78 MAOA (0.50) MAOBMAOAMEN1KMT2APABPC1
SCHEMBL10936171 0.78 MEN1 (0.60) TTRESR1ESR2MAOBMAOA
SCHEMBL17208863 0.77 ELANE (0.49) ESR1ESR2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed