SCHEMBL16601839

SCHEMBL16601839

O=C1c2cccc(-c3ccc(O)cc3)c2C(=O)c2cccc(CCO)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.43
MAOA P21397 3/20 0.42
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
MTOR P42345 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
PABPC1 P11940 1/20 0.38
PTPN1 P18031 1/20 0.37
MAPT P10636 4/20 0.37
LMNA P02545 2/20 0.37
MAPK1 P28482 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAOB P27338 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15764237 0.87 KMT2A (0.43) BACE1MAOAMEN1KMT2APABPC1
SCHEMBL2313485 0.87 MAOA (0.48) MAOANPC1RAB9AMTORMEN1
SCHEMBL16601775 0.86 TTR (0.41) BACE1MAOAMMP2MMP3MMP9
SCHEMBL16601841 0.85 MAOA (0.56) BACE1MAOANPC1RAB9AMEN1
SCHEMBL16656213 0.82 MAOA (0.66) MAOAMEN1KMT2AMAPTLMNA
SCHEMBL2316204 0.82 MEN1 (0.54) MAOARAB9AMEN1KMT2APABPC1
SCHEMBL2311538 0.81 MAOA (0.50) MAOAMEN1KMT2APABPC1MAPT
SCHEMBL16601774 0.81 ADORA2A (0.42) MAOAMEN1KMT2APABPC1MAPT
SCHEMBL9843200 0.80 MAPT (0.52) BACE1MAOANPC1RAB9AMEN1
SCHEMBL16656214 0.78 MAOA (0.70) BACE1MAOAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed