SCHEMBL2311538

SCHEMBL2311538

O=C1c2cccc(CCO)c2C(=O)c2c(CCO)cccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
MAOB P27338 2/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
PABPC1 P11940 1/20 0.45
ELANE P08246 10/20 0.44
CTSG P08311 8/20 0.44
EPHX2 P34913 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2313485 0.94 MAOA (0.48) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL2316204 0.92 MEN1 (0.54) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL16656222 0.91 MAOA (0.67) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL16601845 0.90 ELANE (0.47) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL124078 0.86 ADORA2A (0.52) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL29393629 0.86 ADORA2A (0.52) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL16656213 0.85 MAOA (0.66) MAOAALDH1A1MAPTMAOBTSHR
SCHEMBL15764237 0.84 KMT2A (0.43) MAOAALDH1A1MEN1KMT2APABPC1
SCHEMBL2310241 0.82 MAPT (0.45) MAOAALDH1A1MAPTMAOBMAPK1
SCHEMBL2308920 0.82 MAPT (0.45) MAOAALDH1A1MAPTMAOBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-7989517-B2 Actinic ray curable composition, actinic ray curable ink, and image formation process employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-08-02 US disclosed
US-20070123600-A1 ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, AND IMAGE FORMATION PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-31 US disclosed