Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 4/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134702 | 0.87 | BACE1 (0.73) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL28556962 | 0.77 | BACE1 (0.72) | BACE1CYP3A4TDP1PTPN1PTPRC | |
| SCHEMBL10160580 | 0.76 | BACE1 (0.57) | BACE1CYP3A4PTPN1PTPRCPTPRF | |
| SCHEMBL987908 | 0.73 | BACE1 (1.00) | BACE1PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL24524183 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 | |
| SCHEMBL21392391 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 | |
| Benzidine SCHEMBL308333 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 | |
| Biphenyl-4-Amine SCHEMBL20296849 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 | |
| Biphenyl-4-Amine SCHEMBL15921057 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 | |
| Benzidine SCHEMBL29002343 | 0.72 | CYP3A4 (1.00) | CYP3A4TDP1HSD17B10TAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |