SCHEMBL10160580

SCHEMBL10160580

CC1=CC(=C2C=C(c3ccccc3)C(=O)C(c3ccccc3)=C2)C=C(C)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 0.57
PTPN1 P18031 4/20 0.46
CDC25B P30305 2/20 0.46
PTPRC P08575 1/20 0.46
PTPRF P10586 1/20 0.46
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
IDO1 P14902 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 1/20 0.44
PLIN1 O60240 1/20 0.44
NR1I2 O75469 1/20 0.44
USP2 O75604 1/20 0.44
GSR P00390 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134702 0.87 BACE1 (0.73) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL12112078 0.84 CYP2D6 (0.39) BACE1PTPN1CDC25BALDH1A1MAPT
SCHEMBL16601629 0.84 BACE1 (0.48) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL13903839 0.81 BACE1 (0.39) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL12112067 0.81 PTGS2 (0.38) BACE1CDC25BALDH1A1MAPTMAOA
SCHEMBL12114150 0.77 ALDH1A1 (0.39) ALDH1A1MAOBIDO1GAA
SCHEMBL16601801 0.76 BACE1 (0.57) BACE1PTPN1CDC25BPTPRCPTPRF
SCHEMBL2741115 0.75 ALDH1A1 (0.40) CDC25BALDH1A1MAPTMAOAMAOB
SCHEMBL12112083 0.74 PTPRC (0.57) PTPRCALDH1A1MAPTMAOBLMNA
SCHEMBL987908 0.73 BACE1 (1.00) BACE1PTPN1CDC25BPTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-03-18 US disclosed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US disclosed
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9960360-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960360-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
EP-1950817-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed
EP-1933397-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND FULL COLOR LIGHT-EMITTING DEVICE Idemitsu Kosan Co., Ltd. (JP) 2008-06-18 EP disclosed
US-20080049413-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2008-02-28 US disclosed
US-20080049413-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2008-02-28 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 BACE1 1791/4885PTPN1 4191/4885CDC25B 2070/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 BACE1 3987/4885PTPN1 4212/4885CDC25B 3077/4885
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPL21, RPS21, AOC2 BACE1 1791/4885PTPN1 4191/4885CDC25B 2070/4885
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 BACE1 2644/4885PTPN1 4409/4885CDC25B 3262/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 BACE1 2644/4885PTPN1 4409/4885CDC25B 3262/4885
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 BACE1 2644/4885PTPN1 4409/4885CDC25B 3262/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 BACE1 3987/4885PTPN1 4212/4885CDC25B 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.