Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601983 | 0.86 | KMT2A (0.53) | KMT2AUSP2MEN1NPC1NR1H3 | |
| SCHEMBL16417481 | 0.84 | NR1H2 (0.50) | POLBAPAF1KMT2AUSP2MEN1 | |
| SCHEMBL16601811 | 0.80 | ANPEP (0.50) | POLBKMT2AUSP2MEN1NR1H3 | |
| SCHEMBL16601836 | 0.79 | ALDH1A1 (0.54) | KMT2AUSP2MEN1NPC1RAB9A | |
| SCHEMBL16601772 | 0.79 | NR1H3 (0.50) | POLBKMT2AUSP2MEN1NPC1 | |
| SCHEMBL12577485 | 0.77 | NR1H3 (0.56) | POLBAPAF1KMT2AMEN1NR1H3 | |
| SCHEMBL12556946 | 0.74 | ANPEP (0.55) | POLBKMT2AUSP2MEN1NR1H3 | |
| SCHEMBL29726032 | 0.73 | ALDH1A1 (0.60) | POLBAPAF1KMT2AUSP2MEN1 | |
| SCHEMBL7597251 | 0.73 | ALDH1A1 (0.60) | POLBAPAF1KMT2AUSP2MEN1 | |
| SCHEMBL7602121 | 0.73 | ALDH1A1 (0.60) | POLBAPAF1KMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |